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CG4615 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31656, updated on 10-May-2024

Summary

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Official Symbol
CG4615provided by FlyBase
Primary source
FLYBASE:FBgn0029935
Locus tag
Dmel_CG4615
See related
AllianceGenome:FB:FBgn0029935
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4615
Summary
Predicted to be involved in cytolysis. Predicted to be integral component of membrane. Is expressed in organism. Orthologous to several human genes including MMD (monocyte to macrophage differentiation associated). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG4615 in Genome Data Viewer
Location:
6F5-6F5; 1-19 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7098578..7102300, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6992611..6996333, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Sex lethal Neighboring gene mir-4956 stem loop Neighboring gene long non-coding RNA:CR46494 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene frizzled 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster. Holland C, et al. Genetics, 2011 Jun. PMID 21441212, Free PMC Article
  2. A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease. Nim HT, et al. Genome Biol, 2021 Dec 15. PMID 34906219, Free PMC Article
  3. Identification of Drosophila gene products required for phagocytosis of Candida albicans. Stroschein-Stevenson SL, et al. PLoS Biol, 2006 Jan. PMID 16336044, Free PMC Article
  4. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
  5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables pore-forming activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4615-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    7098578..7102300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132154.3 → NP_572382.1  uncharacterized protein Dmel_CG4615 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572382.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3S5
    Related
    FBpp0070979
    Conserved Domains (1) summary
    TIGR01065
    Location:85 → 304
    hlyIII; channel protein, hemolysin III family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3S5 Q9W3S5

Gene LinkOut

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