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Klhl32 kelch-like family member 32 [ Rattus norvegicus (Norway rat) ]

Gene ID: 313111, updated on 17-Aug-2024

Summary

Official Symbol
Klhl32provided by RGD
Official Full Name
kelch-like family member 32provided by RGD
Primary source
RGD:1310364
See related
EnsemblRapid:ENSRNOG00000007441 AllianceGenome:RGD:1310364
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310364
Summary
Orthologous to human KLHL32 (kelch like family member 32). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 42.1), Adrenal (RPKM 25.0) and 8 other tissues See more
Orthologs
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Genomic context

Location:
5q21
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (43117861..43365080, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (38321237..38568453, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (38968479..39215203, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134478950 Neighboring gene MMS22-like, DNA repair protein Neighboring gene aldo-keto reductase family 1 member B1-like Neighboring gene small nucleolar RNA, H/ACA box 26 Neighboring gene uncharacterized LOC134478952 Neighboring gene glutathione S-transferase P-like Neighboring gene uncharacterized LOC134478951

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
kelch-like family member 32; kelch-like protein 32
Names
kelch-like 32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431161.1NP_001418090.1  kelch-like family member 32 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    F1M9S9
  2. NM_001431162.1NP_001418091.1  kelch-like family member 32 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    F1M9S9
  3. NM_001431163.1NP_001418092.1  kelch-like family member 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A8I6ACF1
  4. NM_001431164.1NP_001418093.1  kelch-like family member 32 isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    43117861..43365080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_232840.11XP_232840.4  kelch-like protein 32 isoform X1

    Related
    ENSRNOP00000091798.2, ENSRNOT00000100722.2
    Conserved Domains (7) summary
    smart00612
    Location:291346
    Kelch; Kelch domain
    smart00875
    Location:144244
    BACK; BTB And C-terminal Kelch
    PHA03098
    Location:30590
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:336384
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:32136
    BTB; BTB/POZ domain
    pfam01344
    Location:483529
    Kelch_1; Kelch motif
    pfam13964
    Location:336388
    Kelch_6; Kelch motif
  2. XM_017593707.3XP_017449196.1  kelch-like protein 32 isoform X4

  3. XM_017593705.2XP_017449194.1  kelch-like protein 32 isoform X2

    Related
    ENSRNOP00000105157.1, ENSRNOT00000148359.1
  4. XM_017593706.2XP_017449195.1  kelch-like protein 32 isoform X3

    Related
    ENSRNOP00000045360.6, ENSRNOT00000050653.8
  5. XM_063261279.1XP_063117349.1  kelch-like protein 32 isoform X5

  6. XM_039110960.2XP_038966888.1  kelch-like protein 32 isoform X7

    Conserved Domains (2) summary
    PHA03098
    Location:66304
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:113161
    Kelch; KELCH repeat [structural motif]
  7. XM_063261280.1XP_063117350.1  kelch-like protein 32 isoform X6

  8. XM_063261281.1XP_063117351.1  kelch-like protein 32 isoform X8