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Tmem254 transmembrane protein 254 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290529, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem254provided by RGD
Official Full Name
transmembrane protein 254provided by RGD
Primary source
RGD:1305689
See related
Ensembl:ENSRNOG00000011276 AllianceGenome:RGD:1305689
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam213a; RGD1305689
Summary
Predicted to be integral component of membrane. Orthologous to human TMEM254 (transmembrane protein 254). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 109.4), Thymus (RPKM 62.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tmem254 in Genome Data Viewer
Location:
16p16
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (1510705..1514591, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (1503931..1507819, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (3817402..3821270)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene placenta associated 9 Neighboring gene uncharacterized LOC134482312 Neighboring gene cytoplasmic polyadenylated homeobox 1 Neighboring gene double homeobox 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC105674

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 254
Names
family with sequence similarity 213, member A
homolog of C10orf57
transmembrane protein C10orf57 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008297.1 → NP_001008298.1  transmembrane protein 254

    See identical proteins and their annotated locations for NP_001008298.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086323
    UniProtKB/Swiss-Prot
    Q5U220
    UniProtKB/TrEMBL
    A6KMI5
    Related
    ENSRNOP00000015011.3, ENSRNOT00000015011.6
    Conserved Domains (1) summary
    pfam14934
    Location:26 → 112
    DUF4499; Domain of unknown function (DUF4499)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    1510705..1514591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006252573.4 → XP_006252635.1  transmembrane protein 254 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JWQ4
    Related
    ENSRNOP00000069971.1
    Conserved Domains (1) summary
    pfam14934
    Location:32 → 118
    DUF4499; Domain of unknown function (DUF4499)

  2. XM_039094246.2 → XP_038950174.1  transmembrane protein 254 isoform X2

    Conserved Domains (1) summary
    pfam14934
    Location:5 → 87
    DUF4499; Domain of unknown function (DUF4499)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5U220.1 GenPept UniProtKB/Swiss-Prot:Q5U220

Gene LinkOut

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