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SERPINF2 serpin family F member 2 [ Bos taurus (cattle) ]

Gene ID: 282522, updated on 5-Mar-2024

Summary

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Official Symbol
SERPINF2provided by VGNC
Official Full Name
serpin family F member 2provided by VGNC
Primary source
VGNC:VGNC:34479
See related
BGD:BT23669; Ensembl:ENSBTAG00000020859
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
PLI
Orthologs
human mouse all
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Genomic context

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See SERPINF2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (22832397..22840458)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene TLC domain containing 2 Neighboring gene microRNA mir-3600 Neighboring gene microRNA mir-22 Neighboring gene WD repeat domain 81 Neighboring gene serpin family F member 1 Neighboring gene SET and MYND domain containing 4 Neighboring gene replication protein A1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Primary structure of bovine alpha 2-antiplasmin. Christensen S, et al. FEBS Lett, 1994 May 2. PMID 7513654
  2. Bovine alpha 2-antiplasmin. N-terminal and reactive site sequence. Christensen S, et al. FEBS Lett, 1992 Nov 2. PMID 1385210
  3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of fibrinolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-2-antiplasmin
Names
alpha-2-AP
alpha-2-PI
alpha-2-plasmin inhibitor
serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
serpin F2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174670.2 → NP_777095.1  alpha-2-antiplasmin precursor

    See identical proteins and their annotated locations for NP_777095.1

    Status: PROVISIONAL

    Source sequence(s)
    X78436
    UniProtKB/Swiss-Prot
    P28800
    Related
    ENSBTAP00000027793.3, ENSBTAT00000027793.5
    Conserved Domains (1) summary
    cd02053
    Location:83 → 434
    alpha2AP; Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    22832397..22840458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024979638.2 → XP_024835406.1  alpha-2-antiplasmin isoform X1

    UniProtKB/Swiss-Prot
    P28800
    Conserved Domains (1) summary
    cd02053
    Location:83 → 434
    alpha2AP; Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin ...

  2. XM_024979639.2 → XP_024835407.1  alpha-2-antiplasmin isoform X2

    Related
    ENSBTAP00000090622.1, ENSBTAT00000133109.1
    Conserved Domains (1) summary
    cd02053
    Location:82 → 433
    alpha2AP; Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin ...

  3. XM_010815811.4 → XP_010814113.1  alpha-2-antiplasmin isoform X2

    Conserved Domains (1) summary
    cd02053
    Location:82 → 433
    alpha2AP; Alpha2-antiplasmin (alpha2AP) is the primary inhibitor of plasmin, a proteinase that digests fibrin, the main component of blood clots. Alpha2-Antiplasmin forms an inactive 1 : 1 stoichiometric complex with plasmin. It also rapidly crosslinks to fibrin ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P28800.2 GenPept UniProtKB/Swiss-Prot:P28800

Gene LinkOut

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