PSMD4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: PSMD4provided by VGNC
Official Full Name: proteasome 26S subunit ubiquitin receptor, non-ATPase 4provided by VGNC
Primary source: VGNC:VGNC:33468
See related: BGD:BT16387; Ensembl:ENSBTAG00000006101
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (19556540..19565662, complement)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables polyubiquitin modification-dependent protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of proteasome regulatory particle, base subcomplex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 4

Names: 26S proteasome regulatory subunit RPN10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; proteasome 26S non-ATPase subunit 4; proteasome 26S subunit, non-ATPase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001013598.2 → NP_001013616.2 26S proteasome non-ATPase regulatory subunit 4

See identical proteins and their annotated locations for NP_001013616.2

Status: VALIDATED

Source sequence(s)

AW655068, BT021757, EV730908

UniProtKB/Swiss-Prot

Q0V8P5, Q58DA0

UniProtKB/TrEMBL

Q0V8N4

Related

ENSBTAP00000008019.7, ENSBTAT00000008019.7

Conserved Domains (1) summary

cd01452
Location:1 → 187

VWA_26S_proteasome_subunit; 26S proteasome plays a major role in eukaryotic protein breakdown, especially for ubiquitin-tagged proteins. It is an ATP-dependent protease responsible for the bulk of non-lysosomal proteolysis in eukaryotes, often using covalent modification of ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

Range

19556540..19565662 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005203837.5 → XP_005203894.1 26S proteasome non-ATPase regulatory subunit 4 isoform X1

UniProtKB/TrEMBL

Q0V8N4

Conserved Domains (1) summary

cd01452
Location:1 → 187

VWA_26S_proteasome_subunit; 26S proteasome plays a major role in eukaryotic protein breakdown, especially for ubiquitin-tagged proteins. It is an ATP-dependent protease responsible for the bulk of non-lysosomal proteolysis in eukaryotes, often using covalent modification of ...