cdc1 DNA polymerase delta small subunit Cdc1 [Schizosaccharomyces pombe (fission yeast)] - Gene

Summary

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Gene symbol: cdc1
Gene description: DNA polymerase delta small subunit Cdc1
Primary source: FungiDB:SPAC27E2.05
Locus tag: SPAC27E2.05
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Schizosaccharomyces pombe (strain: 972h-)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as: mis1
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Genomic context

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See cdc1 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 2

Sequence:: Chromosome: I; NC_003424.3 (4015050..4016557)

Chromosome I - NC_003424.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The E2, J1, J16, J21, J17 and J6 mutations disrupt Cdc1 interactions with both Pol3 and Cdc27 in two hybrid-assays.
Title: Functional mapping of the fission yeast DNA polymerase delta B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by PomBase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA strand elongation involved in DNA replication	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA strand elongation involved in DNA replication	IDA Inferred from Direct Assay more info	PubMed
involved_in DNA synthesis involved in UV-damage excision repair	IDA Inferred from Direct Assay more info	PubMed
involved_in mitotic DNA replication lagging strand elongation	IC Inferred by Curator more info	PubMed
involved_in mitotic DNA replication leading strand elongation	NAS Non-traceable Author Statement more info
involved_in premeiotic DNA replication	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytosol	HDA more info	PubMed
part_of delta DNA polymerase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of delta DNA polymerase complex	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	HDA more info	PubMed

General protein information

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Preferred Names: DNA polymerase delta small subunit Cdc1

NP_594406.1

EC 2.7.7.7

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003424.3 Reference assembly

Range

4015050..4016557

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001019837.2 → NP_594406.1 DNA polymerase delta small subunit Cdc1 [Schizosaccharomyces pombe]

See identical proteins and their annotated locations for NP_594406.1

Status: PROVISIONAL

UniProtKB/Swiss-Prot

P87324

Conserved Domains (2) summary

COG1311
Location:1 → 460

HYS2; Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B [Replication, recombination and repair]

cd07387
Location:185 → 449

MPP_PolD2_C; PolD2 (DNA polymerase delta, subunit 2), C-terminal domain