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sap145 putative U2 snRNP-associated protein Sap145 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541609, updated on 17-May-2024

Summary

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Gene symbol
sap145
Gene description
putative U2 snRNP-associated protein Sap145
Primary source
PomBase:SPAC22F8.10c
Locus tag
SPAC22F8.10c
See related
FungiDB:SPAC22F8.10c; VEuPathDB:SPAC22F8.10c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See sap145 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (4804513..4806453, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene replication termination factor Rtf1 Neighboring gene COPII cargo receptor Sec24/Sfb2 subunit Neighboring gene putative rRNA processing protein Rrp16 Neighboring gene miscRNA Neighboring gene phosphoinositide phospholipase C Plc1 Neighboring gene small histone ubiquitination factor Shf1 Neighboring gene putative CCR4-Not complex subunit Caf16 Neighboring gene formin Fus1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A U1-U2 snRNP interaction network during intron definition. Shao W, et al. Mol Cell Biol, 2012 Jan. PMID 22064476, Free PMC Article
  2. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article
  3. Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Carnahan RH, et al. Eukaryot Cell, 2005 Mar. PMID 15755920, Free PMC Article
  4. Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Livesay SB, et al. Eukaryot Cell, 2013 Nov. PMID 24014766, Free PMC Article
  5. Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes. Chen W, et al. RNA, 2014 Mar. PMID 24442611, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spliceosomal complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U2-type prespliceosome ISO
Inferred from Sequence Orthology
more info
  
part_of U2-type spliceosomal complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of post-mRNA release spliceosomal complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative U2 snRNP-associated protein Sap145

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4804513..4806453 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020161.2 → NP_594733.1  putative U2 snRNP-associated protein Sap145 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594733.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UUI3
    Conserved Domains (4) summary
    smart00581
    Location:328 → 381
    PSP; proline-rich domain in spliceosome associated proteins
    COG5182
    Location:17 → 518
    CUS1; Splicing factor 3b, subunit 2 [RNA processing and modification]
    pfam04037
    Location:198 → 323
    DUF382; Domain of unknown function (DUF382)
    cl12013
    Location:18 → 100
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Protein Accession Links
GenPept Link UniProtKB Link
CAB52720.1

Gene LinkOut

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Molecular Biology Databases
Research Materials