U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

git1 C2 domain protein Git1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540617, updated on 7-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
git1
Gene description
C2 domain protein Git1
Primary source
PomBase:SPBC21C3.20c
Locus tag
SPBC21C3.20c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (3831185..3834493, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene serine/threonine protein kinase Spo4 Neighboring gene putative SBDS family protein Rtc3 Neighboring gene putative mRNA processing factor Neighboring gene putative ATP-dependent DNA helicase Neighboring gene protein N-terminal amidase nta1 Neighboring gene putative U3 snoRNP-associated protein Utp10

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase. Kao RS, et al. Genetics, 2006 May. PMID 16489217, Free PMC Article
  2. Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8). Nocero M, et al. Genetics, 1994 Sep. PMID 8001792, Free PMC Article
  3. The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly. Bao K, et al. PLoS Genet, 2022 Feb. PMID 35171902, Free PMC Article
  4. Six git genes encode a glucose-induced adenylate cyclase activation pathway in the fission yeast Schizosaccharomyces pombe. Byrne SM, et al. J Cell Sci, 1993 Aug. PMID 8227198, Free PMC Article
  5. Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway. Hoffman CS, et al. Genes Dev, 1991 Apr. PMID 1849107

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Git1 is a critical component of the S. pombe glucose/cAMP pathway.
    Title: Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of induction of conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
C2 domain protein Git1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    3831185..3834493 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022520.2 → NP_596600.1  C2 domain protein Git1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596600.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7K5
    Conserved Domains (1) summary
    cl14603
    Location:806 → 900
    C2; C2 domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous