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ent1 epsin [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539390, updated on 17-May-2024

Summary

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Gene symbol
ent1
Gene description
epsin
Primary source
PomBase:SPCC162.07
Locus tag
SPCC162.07
See related
FungiDB:SPCC162.07; VEuPathDB:SPCC162.07
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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See ent1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003421.2 (1571465..1574440, complement)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene putative serine/threonine protein kinase Ppk33 Neighboring gene 3-hydroxy-3-methylglutaryl-CoA reductase Hmg1 Neighboring gene miscRNA Neighboring gene nucleoporin nup211 Neighboring gene putative sorting protein Vps60 Neighboring gene hexaprenyldihydroxybenzoate methyltransferase Coq3 Neighboring gene wtf element Wtf13

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fission yeast epsin, Ent1p is required for endocytosis and involved in actin organization. Sakamoto C, et al. Kobe J Med Sci, 2004 Jan. PMID 15659877
  2. Actin filament severing by cofilin dismantles actin patches and produces mother filaments for new patches. Chen Q, et al. Curr Biol, 2013 Jul 8. PMID 23727096, Free PMC Article
  3. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
  4. SR protein kinases promote splicing of nonconsensus introns. Lipp JJ, et al. Nat Struct Mol Biol, 2015 Aug. PMID 26167880
  5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables clathrin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-4,5-bisphosphate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables phospholipid binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in actin cortical patch assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in actin cortical patch IDA
Inferred from Direct Assay
more info
 PubMed 
part_of clathrin vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
epsin

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1571465..1574440 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023227.2 → NP_588237.1  epsin [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588237.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O74423
    Conserved Domains (4) summary
    cd03571
    Location:21 → 143
    ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
    pfam05672
    Location:234 → 289
    MAP7; MAP7 (E-MAP-115) family
    pfam06625
    Location:230 → 289
    DUF1151; Protein of unknown function (DUF1151)
    pfam08226
    Location:349 → 428
    DUF1720; Domain of unknown function (DUF1720)
Protein Accession Links
GenPept Link UniProtKB Link
CAA19587.1

Gene LinkOut

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