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K07E8.6 Cdc37 Hsp90 binding domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 187114, updated on 18-Sep-2024

Summary

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Official Symbol
K07E8.6
Official Full Name
Cdc37 Hsp90 binding domain-containing protein
Primary source
WormBase:WBGene00019497
Locus tag
CELE_K07E8.6
See related
AllianceGenome:WB:WBGene00019497
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable chaperone binding activity; heat shock protein binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding and protein stabilization. Predicted to be active in cytoplasm. Orthologous to human CDC37L1 (cell division cycle 37 like 1) and CDC37 (cell division cycle 37, HSP90 cochaperone). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See K07E8.6 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003280.10 (637318..639567, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene Pseudouridine synthase Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-folding chaperone binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein stabilization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cdc37 Hsp90 binding domain-containing protein
NP_001254017.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    637318..639567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001267088.3 → NP_001254017.1  Cdc37 Hsp90 binding domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001254017.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L0F2
    Conserved Domains (1) summary
    cl07248
    Location:78 → 197
    CDC37_M; Cdc37 Hsp90 binding domain

RNA

  1. NR_133627.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

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