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C09F9.2 EGF-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182456, updated on 18-Sep-2024

Summary

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Official Symbol
C09F9.2
Official Full Name
EGF-like domain-containing protein
Primary source
WormBase:WBGene00007479
Locus tag
CELE_C09F9.2
See related
AllianceGenome:WB:WBGene00007479
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (14705515..14713240)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene DUF148 domain-containing protein;Phage protein Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  2. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
EGF-like domain-containing protein
NP_497053.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    14705515..14713240
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064652.3 → NP_497053.1  EGF-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497053.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62055
    Conserved Domains (3) summary
    smart00664
    Location:592 → 745
    DoH; Possible catecholamine-binding domain present in a variety of eukaryotic proteins
    pfam01826
    Location:393 → 447
    TIL; Trypsin Inhibitor like cysteine rich domain
    cl02507
    Location:1347 → 1431
    SEA; SEA domain
Nucleotide Protein
Heading Accession and Version

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