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F47E1.2 Solute carrier organic anion transporter family member [ Caenorhabditis elegans ]

Gene ID: 181145, updated on 2-Nov-2024

Summary

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Official Symbol
F47E1.2
Official Full Name
Solute carrier organic anion transporter family member
Primary source
WormBase:WBGene00018566
Locus tag
CELE_F47E1.2
See related
AllianceGenome:WB:WBGene00018566
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder and gastrointestinal stromal tumor. Orthologous to several human genes including SLCO3A1 (solute carrier organic anion transporter family member 3A1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See F47E1.2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (9057652..9061860)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene Solute carrier organic anion transporter family member Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Solute carrier organic anion transporter family member
NP_509531.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    9057652..9061860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077130.8 → NP_509531.1  Solute carrier organic anion transporter family member [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509531.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20538
    Conserved Domains (4) summary
    cd06174
    Location:8 → 92
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:528 → 583
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    TIGR00805
    Location:95 → 715
    oat; sodium-independent organic anion transporter
    cl21472
    Location:274 → 503
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
Nucleotide Protein
Heading Accession and Version

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