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F53E4.1 Kelch domain-containing protein 10;Kelch domain-containing protein 3 [ Caenorhabditis elegans ]

Gene ID: 180050, updated on 23-Nov-2023

Summary

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Gene symbol
F53E4.1
Gene description
Kelch domain-containing protein 10;Kelch domain-containing protein 3
Primary source
WormBase:WBGene00009978
Locus tag
CELE_F53E4.1
See related
AllianceGenome:WB:WBGene00009978
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable chromatin binding activity. Predicted to be active in cytoplasm. Is expressed in several structures, including arcade cell; hypodermis; intestine; nervous system; and reproductive system. Orthologous to human KLHDC3 (kelch domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See F53E4.1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
9
Sequence:
Chromosome: V; NC_003283.11 (15652430..15668300, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DUF148 domain-containing protein Neighboring gene Serpentine receptor class gamma Neighboring gene Ovule protein Neighboring gene Conserved plasma membrane protein Neighboring gene DUF1084 domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Kelch domain-containing protein 10;Kelch domain-containing protein 3
NP_001122948.1
  • Confirmed by transcript evidence
NP_001256679.1
  • Confirmed by transcript evidence
NP_001368706.1
  • Partially confirmed by transcript evidence
NP_001379191.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    15652430..15668300 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129476.5 → NP_001122948.1  Kelch domain-containing protein 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122948.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EBG8
    Conserved Domains (3) summary
    sd00038
    Location:144 → 186
    Kelch; KELCH repeat [structural motif]
    pfam07646
    Location:93 → 134
    Kelch_2; Kelch motif
    pfam13415
    Location:153 → 204
    Kelch_3; Galactose oxidase, central domain

  2. NM_001392674.1 → NP_001379191.1  Kelch domain-containing protein 3 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EEG5
    Conserved Domains (3) summary
    PLN02153
    Location:73 → 332
    PLN02153; epithiospecifier protein
    sd00038
    Location:144 → 186
    Kelch; KELCH repeat [structural motif]
    pfam07646
    Location:13 → 61
    Kelch_2; Kelch motif

  3. NM_001380833.1 → NP_001368706.1  Kelch domain-containing protein 3 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A3B1E9Z3
    Conserved Domains (3) summary
    PLN02153
    Location:79 → 338
    PLN02153; epithiospecifier protein
    sd00038
    Location:150 → 192
    Kelch; KELCH repeat [structural motif]
    pfam07646
    Location:19 → 67
    Kelch_2; Kelch motif

  4. NM_001269750.3 → NP_001256679.1  Kelch domain-containing protein 10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256679.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    H9G305
    Conserved Domains (2) summary
    sd00038
    Location:25 → 74
    Kelch; KELCH repeat [structural motif]
    pfam13415
    Location:34 → 84
    Kelch_3; Galactose oxidase, central domain
Nucleotide Protein
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