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tag-120 Transmembrane BAX inhibitor motif-containing protein 4 [ Caenorhabditis elegans ]

Gene ID: 179362, updated on 25-Apr-2024

Summary

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Gene symbol
tag-120
Gene description
Transmembrane BAX inhibitor motif-containing protein 4
Primary source
WormBase:WBGene00006470
Locus tag
CELE_F40F9.2
See related
AllianceGenome:WB:WBGene00006470
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in excretory system; neurons; and pharyngeal muscle cell. Orthologous to several human genes including FAIM2 (Fas apoptotic inhibitory molecule 2) and TMBIM1 (transmembrane BAX inhibitor motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See tag-120 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (9707771..9709814, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene RNA_ligase domain-containing protein Neighboring gene Protein her-1 Neighboring gene Protein lifeguard 1-like Neighboring gene tRNA wybutosine-synthesizing protein 2 homolog Neighboring gene ncRNA Neighboring gene PDZ domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in negative regulation of apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Transmembrane BAX inhibitor motif-containing protein 4
NP_505501.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    9707771..9709814 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073100.9 → NP_505501.1  Transmembrane BAX inhibitor motif-containing protein 4 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505501.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q20241
    Conserved Domains (1) summary
    cd10428
    Location:21 → 241
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis
Nucleotide Protein
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