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catp-3 Cation-transporting P-type ATPase N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 179189, updated on 18-Sep-2024

Summary

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Official Symbol
catp-3
Official Full Name
Cation-transporting P-type ATPase N-terminal domain-containing protein
Primary source
WormBase:WBGene00015660
Locus tag
CELE_C09H5.2
See related
AllianceGenome:WB:WBGene00015660
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable P-type sodium:potassium-exchanging transporter activity. Acts upstream of or within IRE1-mediated unfolded protein response. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit) and ATP4A (ATPase H+/K+ transporting subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (8076012..8079916)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Seven TM Receptor Neighboring gene Seven TM Receptor Neighboring gene Seven TM Receptor Neighboring gene Serine/threonine-protein phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The DNA damage-inducible C. elegans tankyrase is a nuclear protein closely linked to chromosomes. White C, et al. Mol Cell Biochem, 2009 Apr. PMID 19104912
  2. F-actin asymmetry and the endoplasmic reticulum-associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo. Berends CW, et al. Mol Biol Cell, 2013 Jul. PMID 23699393, Free PMC Article
  3. Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure. Boyd WA, et al. Mutat Res, 2010 Jan 5. PMID 19879883, Free PMC Article
  4. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. Troemel ER, et al. PLoS Genet, 2006 Nov 10. PMID 17096597, Free PMC Article
  5. Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans. Shen X, et al. PLoS Genet, 2005 Sep. PMID 16184190, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables P-type sodium:potassium-exchanging transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within IRE1-mediated unfolded protein response HEP PubMed 
involved_in establishment or maintenance of transmembrane electrochemical gradient IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular potassium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular sodium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proton transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion export across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Cation-transporting P-type ATPase N-terminal domain-containing protein
NP_505083.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8076012..8079916
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072682.5 → NP_505083.1  Cation-transporting P-type ATPase N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505083.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16331
    Conserved Domains (1) summary
    cl21460
    Location:66 → 1044
    HAD_like; Haloacid Dehalogenase-like Hydrolases

RNA

  1. NR_136356.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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