nhr-114 Nuclear hormone receptor 114 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: nhr-114
Official Full Name: Nuclear hormone receptor 114
Primary source: WormBase:WBGene00003704
Locus tag: CELE_Y45G5AM.1
See related: AllianceGenome:WB:WBGene00003704
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in regulation of gene expression. Acts upstream of with a positive effect on S-adenosylmethionine cycle. Located in nucleus. Is expressed in germ line; hypodermis; and intestine. [provided by Alliance of Genome Resources, Apr 2022]
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Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

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Fertility and germline stem cell maintenance under different diets requires nhr-114/HNF4 in C. elegans.
Title: Fertility and germline stem cell maintenance under different diets requires nhr-114/HNF4 in C. elegans.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nuclear receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_positive_effect S-adenosylmethionine cycle	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

NP_001024242.1

NP_001317845.1

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The following sections contain reference sequences that belong to a specific genome build. Explain