noah-2 PAN domain protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: noah-2
Official Full Name: PAN domain protein
Primary source: WormBase:WBGene00009926
Locus tag: CELE_F52B11.3
See related: AllianceGenome:WB:WBGene00009926
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in molting cycle. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in hypodermis. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See noah-2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 5

Sequence:: Chromosome: IV; NC_003282.8 (14091254..14096626)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Noah2 gene is required for nonsense-mediated mRNA decay pathway and proper development in C. elegans.
Title: Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS4-197 (e-PCR)
- UniSTS:242187

F52B11.3 (e-PCR)
- UniSTS:312609

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in molting cycle, collagen and cuticulin-based cuticle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: PAN domain protein

NP_502699.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

14091254..14096626

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_070298.7 → NP_502699.1 PAN domain protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_502699.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9XUE5

Conserved Domains (3) summary

smart00241
Location:392 → 634

ZP; Zona pellucida (ZP) domain

cd01099
Location:125 → 203

PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...

pfam00024
Location:310 → 382

PAN_1; PAN domain