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egl-23 Potassium channel domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 178358, updated on 18-Sep-2024

Summary

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Official Symbol
egl-23
Official Full Name
Potassium channel domain-containing protein
Primary source
WormBase:WBGene00001190
Locus tag
CELE_Y37A1B.11
See related
AllianceGenome:WB:WBGene00001190
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
14
Sequence:
Chromosome: IV; NC_003282.8 (13989081..14012074)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA-Ala

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reversal of a muscle response to GABA during C. elegans male development. Reiner DJ, et al. J Neurosci, 1995 Sep. PMID 7666193, Free PMC Article
  2. Potassium channels in C. elegans. Salkoff L, et al. WormBook, 2005 Dec 30. PMID 18050399, Free PMC Article
  3. Characterization of a germ-line proliferation mutation in C. elegans. Beanan MJ, et al. Development, 1992 Nov. PMID 1289064
  4. Analysis of dominant mutations affecting muscle excitation in Caenorhabditis elegans. Reiner DJ, et al. Genetics, 1995 Nov. PMID 8582640, Free PMC Article
  5. Structure and function of two-pore-domain K+ channels: contributions from genetic model organisms. Buckingham SD, et al. Trends Pharmacol Sci, 2005 Jul. PMID 15939489

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables outward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables potassium ion leak channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Potassium channel domain-containing protein
NP_001255775.1
  • Confirmed by transcript evidence
NP_001255776.1
  • Confirmed by transcript evidence
NP_001293999.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13989081..14012074
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268846.3 → NP_001255775.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255775.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    C0Z3L1
    Conserved Domains (1) summary
    pfam07885
    Location:217 → 275
    Ion_trans_2; Ion channel

  2. NM_001307070.3 → NP_001293999.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293999.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A061AL62
    Conserved Domains (2) summary
    pfam07885
    Location:174 → 234
    Ion_trans_2; Ion channel
    pfam09404
    Location:84 → 185
    DUF2003; Eukaryotic protein of unknown function (DUF2003)

  3. NM_001268847.4 → NP_001255776.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255776.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XXF6
    Conserved Domains (1) summary
    pfam07885
    Location:181 → 241
    Ion_trans_2; Ion channel
Nucleotide Protein
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