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thoc-7 THO complex subunit 7 homolog [ Caenorhabditis elegans ]

Gene ID: 178353, updated on 18-Sep-2024

Summary

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Official Symbol
thoc-7
Official Full Name
THO complex subunit 7 homolog
Primary source
WormBase:WBGene00007195
Locus tag
CELE_B0513.2
See related
AllianceGenome:WB:WBGene00007195
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Orthologous to human THOC7 (THO complex 7). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: IV
Exon count:
5
Sequence:
Chromosome: IV; NC_003282.8 (13882734..13884177)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Transposase Neighboring gene 60S ribosomal protein L29 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Caenorhabditis elegans THO complex is required for the mitotic cell cycle and development. Castellano-Pozo M, et al. PLoS One, 2012. PMID 23285047, Free PMC Article
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of THO complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of THO complex part of transcription export complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of THO complex part of transcription export complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
THO complex subunit 7 homolog
NP_001255765.1
  • Confirmed by transcript evidence
NP_001255766.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13882734..13884177
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268836.4 → NP_001255765.1  THO complex subunit 7 homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U3S3
    Conserved Domains (1) summary
    pfam05615
    Location:3 → 131
    THOC7; Tho complex subunit 7

  2. NM_001268837.3 → NP_001255766.1  THO complex subunit 7 homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3YT70
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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