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ints-13 Protein asunder [ Caenorhabditis elegans ]

Gene ID: 176839, updated on 2-Nov-2024

Summary

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Official Symbol
ints-13
Official Full Name
Protein asunder
Primary source
WormBase:WBGene00019822
Locus tag
CELE_R02D3.4
See related
AllianceGenome:WB:WBGene00019822
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in centrosome localization and regulation of mitotic cell cycle. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be part of integrator complex. Orthologous to human INTS13 (integrator complex subunit 13). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ints-13 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (232473..237450, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Thioredoxin domain-containing protein Neighboring gene BSD domain-containing protein Neighboring gene Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Neighboring gene Conserved oligomeric Golgi complex subunit 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes. Gómez-Orte E, et al. PLoS Genet, 2019 Feb. PMID 30807579, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in centrosome localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of integrator complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein asunder
NP_001368353.1
  • Confirmed by transcript evidence
NP_001368354.1
  • Confirmed by transcript evidence
NP_499881.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    232473..237450 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_067480.5 → NP_499881.1  Protein asunder [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499881.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44500
    Conserved Domains (1) summary
    pfam10221
    Location:2 → 744
    DUF2151; Cell cycle and development regulator

  2. NM_001379999.1 → NP_001368353.1  Protein asunder [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PCN0
    Conserved Domains (1) summary
    pfam10221
    Location:1 → 482
    DUF2151; Cell cycle and development regulator

  3. NM_001380000.1 → NP_001368354.1  Protein asunder [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PN35
    Conserved Domains (1) summary
    pfam10221
    Location:8 → 299
    DUF2151; Cell cycle and development regulator
Nucleotide Protein
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