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lin-36 Protein lin-36 [ Caenorhabditis elegans ]

Gene ID: 176128, updated on 18-Sep-2024

Summary

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Official Symbol
lin-36
Official Full Name
Protein lin-36
Primary source
WormBase:WBGene00003021
Locus tag
CELE_F44B9.6
See related
AllianceGenome:WB:WBGene00003021
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Involved in embryonic digestive tract morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; neurons; and vulval cell. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
10
Sequence:
Chromosome: III; NC_003281.10 (8016648..8020873, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Cyclin-T1.1 Neighboring gene Cyclin-T1.2 Neighboring gene Lipid droplet-regulating VLDL assembly factor AUP1 homolog Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Glutamine/asparagine-rich protein mdt-30

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The C. elegans gene lin-9,which acts in an Rb-related pathway, is required for gonadal sheath cell development and encodes a novel protein. Beitel GJ, et al. Gene, 2000 Aug 22. PMID 10974557
  2. Reading the worm genome. Kim SK. Science, 2000 Jan 7. PMID 10644223
  3. The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins. Clark SG, et al. Genetics, 1994 Aug. PMID 7982579, Free PMC Article
  4. The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways. Ferguson EL, et al. Genetics, 1989 Sep. PMID 2806880, Free PMC Article
  5. lin-35/Rb and xnp-1/ATR-X function redundantly to control somatic gonad development in C. elegans. Bender AM, et al. Dev Biol, 2004 Sep 15. PMID 15328017

See all (54) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in embryonic digestive tract morphogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein lin-36
NP_498747.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    8016648..8020873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066346.7 → NP_498747.2  Protein lin-36 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498747.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34427, Q9U552
    Conserved Domains (1) summary
    pfam15769
    Location:749 → 871
    DUF4698; Domain of unknown function (DUF4698)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34427.2

Gene LinkOut

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