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ZK686.2 Putative ATP-dependent RNA helicase ZK686.2 [ Caenorhabditis elegans ]

Gene ID: 176088, updated on 18-Sep-2024

Summary

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Official Symbol
ZK686.2
Official Full Name
Putative ATP-dependent RNA helicase ZK686.2
Primary source
WormBase:WBGene00022792
Locus tag
CELE_ZK686.2
See related
AllianceGenome:WB:WBGene00022792
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be active in nucleus. Is expressed in neurons. Orthologous to human DDX51 (DEAD-box helicase 51). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (7763720..7766052, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Putative serine protease pcp-1 Neighboring gene Metaxin-2 homolog Neighboring gene Putative zinc finger protein ZK686.5 Neighboring gene putative dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables helicase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in P granule IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Putative ATP-dependent RNA helicase ZK686.2
NP_498690.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7763720..7766052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066289.7 → NP_498690.2  Putative ATP-dependent RNA helicase ZK686.2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498690.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34668
    Conserved Domains (3) summary
    smart00487
    Location:130 → 352
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:371 → 502
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00270
    Location:135 → 330
    DEAD; DEAD/DEAH box helicase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34668.2

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