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ins-17 Insulin-like peptide 17 [ Caenorhabditis elegans ]

Gene ID: 175585, updated on 18-Sep-2024

Summary

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Official Symbol
ins-17
Official Full Name
Insulin-like peptide 17
Primary source
WormBase:WBGene00002100
Locus tag
CELE_F56F3.6
See related
AllianceGenome:WB:WBGene00002100
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in dauer larval development. Predicted to be located in extracellular region. Is expressed in several structures, including coelomocyte; egg-laying apparatus; gonad; head; and nervous system. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003281.10 (4476918..4477572, complement)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein eS1 Neighboring gene Chondroitin proteoglycan 1 Neighboring gene Transcription factor atf-7 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Caenorhabditis elegans insulin-like peptide, INS-17: its physiological function and expression pattern. Matsunaga Y, et al. Biosci Biotechnol Biochem, 2012. PMID 23132577
  2. Identification and analysis of insulin like peptides in nematode secretomes provide targets for parasite control. Gahoi S, et al. Bioinformation, 2016. PMID 28356679, Free PMC Article
  3. Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson's disease. Haque R, et al. Oncotarget, 2020 Feb 11. PMID 32110282, Free PMC Article
  4. Dauer signalling pathway model for Haemonchus contortus. Ma G, et al. Parasit Vectors, 2019 Apr 29. PMID 31036054, Free PMC Article
  5. Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host. Ma G, et al. Parasit Vectors, 2019 Jan 14. PMID 30642380, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. physiological function and expression pattern of INS-17
    Title: A Caenorhabditis elegans insulin-like peptide, INS-17: its physiological function and expression pattern.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in dauer larval development IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Insulin-like peptide 17
NP_497911.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    4476918..4477572 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065510.8 → NP_497911.1  Insulin-like peptide 17 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497911.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EFH1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G5EFH1.1

Gene LinkOut

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