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F33A8.4 CTCHY-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 174691, updated on 18-Sep-2024

Summary

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Official Symbol
F33A8.4
Official Full Name
CTCHY-type domain-containing protein
Primary source
WormBase:WBGene00009352
Locus tag
CELE_F33A8.4
See related
AllianceGenome:WB:WBGene00009352
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable rRNA (adenine-N6-)-methyltransferase activity. Predicted to be involved in rRNA methylation. Predicted to be active in cytoplasm and nucleolus. Orthologous to human ZCCHC4 (zinc finger CCHC-type containing 4). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
7
Sequence:
Chromosome: II; NC_003280.10 (11045786..11049030, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SXP/RAL-2 family protein Ani s 5-like cation-binding domain-containing protein Neighboring gene CSD domain-containing protein Neighboring gene ncRNA Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial Neighboring gene PPM-type phosphatase domain-containing protein Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (adenine-N6-)-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA (adenine-N6-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA methylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
CTCHY-type domain-containing protein
NP_496368.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    11045786..11049030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063967.5 → NP_496368.1  CTCHY-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496368.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62214
    Conserved Domains (2) summary
    pfam10237
    Location:210 → 361
    N6-adenineMlase; Probable N6-adenine methyltransferase
    pfam12675
    Location:404 → 452
    DUF3795; Protein of unknown function (DUF3795)
Nucleotide Protein
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