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gly-1 Core-2/I-Branching enzyme [ Caenorhabditis elegans ]

Gene ID: 174679, updated on 25-Apr-2024

Summary

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Gene symbol
gly-1
Gene description
Core-2/I-Branching enzyme
Primary source
WormBase:WBGene00001626
Locus tag
CELE_F44F4.6
See related
AllianceGenome:WB:WBGene00001626
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable acetylglucosaminyltransferase activity. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Is expressed in seam cell. Human ortholog(s) of this gene implicated in cataract and cataract 13 with adult i phenotype. Orthologous to human GCNT2 (glucosaminyl (N-acetyl) transferase 2 (I blood group)). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See gly-1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
8
Sequence:
Chromosome: II; NC_003280.10 (10899985..10902204, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SSD domain-containing protein Neighboring gene Serpentine receptor class alpha-10 Neighboring gene Serpentine receptor class alpha-12 Neighboring gene Serpentine receptor class alpha-11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Complementary expression patterns of six nonessential Caenorhabditis elegans core 2/I N-acetylglucosaminyltransferase homologues. Warren CE, et al. Glycobiology, 2001 Nov. PMID 11744632
  2. Carbohydrates and glycosylation. Berninsone PM. WormBook, 2006 Dec 18. PMID 18050430, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Core-2/I-Branching enzyme
NP_496345.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    10899985..10902204 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063944.8 → NP_496345.1  Core-2/I-Branching enzyme [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496345.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5ECK8
    Conserved Domains (1) summary
    pfam02485
    Location:129 → 321
    Branch; Core-2/I-Branching enzyme
Nucleotide Protein
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