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K10B4.3 Protein melted homolog [ Caenorhabditis elegans ]

Gene ID: 173397, updated on 18-Sep-2024

Summary

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Official Symbol
K10B4.3
Official Full Name
Protein melted homolog
Primary source
WormBase:WBGene00019615
Locus tag
CELE_K10B4.3
See related
AllianceGenome:WB:WBGene00019615
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphatidylinositol-5-phosphate binding activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human VEPH1 (ventricular zone expressed PH domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
10
Sequence:
Chromosome: II; NC_003280.10 (114428..121221, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene PDZ domain-containing protein Neighboring gene Cationic amino acid transporter C-terminal domain-containing protein Neighboring gene Ntox44 domain-containing protein;Peptidase S1 domain-containing protein Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Neuromedin U receptor homolog nmur-2 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphatidylinositol-5-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Protein melted homolog
NP_493664.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    114428..121221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061263.5 → NP_493664.2  Protein melted homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493664.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O17237
    Conserved Domains (2) summary
    pfam00169
    Location:759 → 864
    PH; PH domain
    cl17171
    Location:757 → 869
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O17237.3

Gene LinkOut

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