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sqt-2 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 173382, updated on 18-Sep-2024

Summary

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Official Symbol
sqt-2
Official Full Name
Nematode cuticle collagen N-terminal domain-containing protein
Primary source
WormBase:WBGene00005017
Locus tag
CELE_C01B12.1
See related
AllianceGenome:WB:WBGene00005017
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Predicted to be located in membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003280.10 (23325..24458)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SAND domain-containing protein Neighboring gene ncRNA Neighboring gene Coiled-coil domain-containing protein 86 Neighboring gene Uncharacterized protein Neighboring gene Snurportin-1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. WormSizer: high-throughput analysis of nematode size and shape. Moore BT, et al. PLoS One, 2013. PMID 23451165, Free PMC Article
  2. Cuticle chirality and body handedness in Caenorhabditis elegans. Bergmann DC, et al. Dev Genet, 1998. PMID 9842711
  3. Genes that can be mutated to unmask hidden antigenic determinants in the cuticle of the nematode Caenorhabditis elegans. Politz SM, et al. Proc Natl Acad Sci U S A, 1990 Apr. PMID 1691498, Free PMC Article
  4. Genetic studies of unusual loci that affect body shape of the nematode Caenorhabditis elegans and may code for cuticle structural proteins. Kusch M, et al. Genetics, 1986 Jul. PMID 3732788, Free PMC Article
  5. Genetic and Phenotypic Characterization of Roller Mutants of CAENORHABDITIS ELEGANS. Cox GN, et al. Genetics, 1980 Jun. PMID 17249038, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables structural constituent of cuticle IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cuticle development involved in collagen and cuticulin-based cuticle molting cycle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nematode cuticle collagen N-terminal domain-containing protein
NP_493635.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    23325..24458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061234.6 → NP_493635.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493635.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17209
    Conserved Domains (2) summary
    pfam01391
    Location:205 → 265
    Collagen; Collagen triple helix repeat (20 copies)
    smart01088
    Location:12 → 64
    Col_cuticle_N; Nematode cuticle collagen N-terminal domain
Nucleotide Protein
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