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ZNF578 zinc finger protein 578 [ Homo sapiens (human) ]

Gene ID: 147660, updated on 26-May-2016
Official Symbol
ZNF578provided by HGNC
Official Full Name
zinc finger protein 578provided by HGNC
Primary source
HGNC:HGNC:26449
See related
Ensembl:ENSG00000258405 HPRD:15857; Vega:OTTHUMG00000156468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
Location:
19q13.41
Exon count:
11
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 19 NC_000019.10 (52453506..52516878)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (52956829..53020131)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 610 pseudogene Neighboring gene zinc finger protein 534 Neighboring gene DUT pseudogene Neighboring gene zinc finger protein 347 pseudogene Neighboring gene zinc finger protein 808 Neighboring gene ribosomal protein L39 pseudogene 34 Neighboring gene zinc finger protein 701

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ31384

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099694.1NP_001093164.1  zinc finger protein 578

    See identical proteins and their annotated locations for NP_001093164.1

    Status: VALIDATED

    Source sequence(s)
    AC022150, AK055946, BC115704, BX955279
    Consensus CDS
    CCDS54310.1
    UniProtKB/Swiss-Prot
    Q96N58
    UniProtKB/TrEMBL
    Q3MI94
    Related
    ENSP00000459216, OTTHUMP00000256866, ENST00000421239, OTTHUMT00000344298
    Conserved Domains (5) summary
    cd07765
    Location:2460
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:2471
    KRAB; krueppel associated box
    COG5048
    Location:257582
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:469494
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:373393
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p2 Primary Assembly

    Range
    52453506..52516878
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526470.1XP_011524772.1  

    Conserved Domains (3) summary
    COG5048
    Location:188517
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:400425
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:304324
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_005258527.2XP_005258584.1  

    See identical proteins and their annotated locations for XP_005258584.1

    UniProtKB/Swiss-Prot
    Q96N58
    Conserved Domains (5) summary
    cd07765
    Location:2460
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:2471
    KRAB; krueppel associated box
    COG5048
    Location:257582
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:469494
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:373393
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_011526467.1XP_011524769.1  

    See identical proteins and their annotated locations for XP_011524769.1

    UniProtKB/Swiss-Prot
    Q96N58
    Conserved Domains (5) summary
    cd07765
    Location:2460
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:2471
    KRAB; krueppel associated box
    COG5048
    Location:257582
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:469494
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:373393
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_006723020.2XP_006723083.1  

    See identical proteins and their annotated locations for XP_006723083.1

    UniProtKB/Swiss-Prot
    Q96N58
    Conserved Domains (5) summary
    cd07765
    Location:2460
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:2471
    KRAB; krueppel associated box
    COG5048
    Location:257582
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:469494
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:373393
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_006723019.2XP_006723082.1  

    See identical proteins and their annotated locations for XP_006723082.1

    UniProtKB/Swiss-Prot
    Q96N58
    Conserved Domains (5) summary
    cd07765
    Location:2460
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:2471
    KRAB; krueppel associated box
    COG5048
    Location:257582
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:469494
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:373393
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_011526468.1XP_011524770.1  

    See identical proteins and their annotated locations for XP_011524770.1

    UniProtKB/Swiss-Prot
    Q96N58
    Conserved Domains (5) summary
    cd07765
    Location:2460
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:2471
    KRAB; krueppel associated box
    COG5048
    Location:257582
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:469494
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:373393
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_011526469.1XP_011524771.1  

    See identical proteins and their annotated locations for XP_011524771.1

    UniProtKB/Swiss-Prot
    Q96N58
    Conserved Domains (5) summary
    cd07765
    Location:2460
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
    smart00349
    Location:2471
    KRAB; krueppel associated box
    COG5048
    Location:257582
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:469494
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:373393
    ZF_C2H2; C2H2 Zn finger [structural motif]

Alternate CHM1_1.1

Genomic

  1. NC_018930.2 Alternate CHM1_1.1

    Range
    52958517..53021908
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_152472.1: Suppressed sequence

    Description
    NM_152472.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.