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rad50 DNA double-strand break repair ATPase Rad50 [ Halobacterium salinarum NRC-1 ]

Gene ID: 1447348, updated on 17-Jun-2024

Summary

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Gene symbol
rad50
Gene description
DNA double-strand break repair ATPase Rad50
Locus tag
VNG_RS02010
Gene type
protein coding
Organism
Halobacterium salinarum NRC-1 (strain: NRC-1; ATCC 700922, culture-collection: ATCC:700922)
Lineage
Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium
Old locus tag
VNG0514C; VNG_0514C
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Genomic context

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Sequence:
NC_002607.1 (397105..399756)

NC_002607.1Genomic Context describing neighboring genes Neighboring gene proteasome-activating nucleotidase Neighboring gene winged helix-turn-helix transcriptional regulator Neighboring gene DNA double-strand break repair protein Mre11 Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002607.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rad50 is not essential for the Mre11-dependent repair of DNA double-strand breaks in Halobacterium sp. strain NRC-1. Kish A, et al. J Bacteriol, 2008 Aug. PMID 18502851, Free PMC Article
  2. Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination. Delmas S, et al. PLoS Genet, 2009 Jul. PMID 19593371, Free PMC Article
  3. A manual curation strategy to improve genome annotation: application to a set of haloarchael genomes. Pfeiffer F, et al. Life (Basel), 2015 Jun 2. PMID 26042526, Free PMC Article
  4. Genome sequence of Halobacterium species NRC-1. Ng WV, et al. Proc Natl Acad Sci U S A, 2000 Oct 24. PMID 11016950, Free PMC Article
  5. Evolution in the laboratory: the genome of Halobacterium salinarum strain R1 compared to that of strain NRC-1. Pfeiffer F, et al. Genomics, 2008 Apr. PMID 18313895

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These observations led to the hypothesis that Mre11 is essential for the repair of DNA double-strand breaks in Halobacterium, whereas Rad50 is dispensable.
    Title: Rad50 is not essential for the Mre11-dependent repair of DNA double-strand breaks in Halobacterium sp. strain NRC-1.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
DNA double-strand break repair ATPase Rad50

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002607.1 Reference assembly

    Range
    397105..399756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_010902341.1 DNA double-strand break repair ATPase Rad50 [Halobacterium salinarum]

    See identical proteins and their annotated locations for WP_010902341.1

    UniProtKB/Swiss-Prot
    Q9HRW3
    UniProtKB/TrEMBL
    A0A4D6GVH3, A0A510N4X7, A0A841HBY2, B0R3J3
    Conserved Domains (1) summary
    PRK02224
    Location:1 → 880
    PRK02224; DNA double-strand break repair Rad50 ATPase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9HRW3.1

Gene LinkOut

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