Format

Send to:

Choose Destination

Cradd CASP2 and RIPK1 domain containing adaptor with death domain [ Mus musculus (house mouse) ]

Gene ID: 12905, updated on 15-May-2016
Official Symbol
Craddprovided by MGI
Official Full Name
CASP2 and RIPK1 domain containing adaptor with death domainprovided by MGI
Primary source
MGI:MGI:1336168
See related
Ensembl:ENSMUSG00000045867
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RAIDD
Orthologs
Location:
10 C2; 10 49.26 cM
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (95174739..95324345, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (94637380..94786731, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 33091 Neighboring gene predicted gene, 29684 Neighboring gene RIKEN cDNA 2310039L15 gene Neighboring gene predicted gene, 33188 Neighboring gene suppressor of cytokine signaling 2 Neighboring gene predicted gene, 33230

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
death domain binding ISO
Inferred from Sequence Orthology
more info
 
protease binding ISO
Inferred from Sequence Orthology
more info
 
protein binding, bridging ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ISO
Inferred from Sequence Orthology
more info
 
activation of cysteine-type endopeptidase activity involved in apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
death domain-containing protein CRADD
Names
CASP2 and RIPK1 domain-containing adaptor with death domain
RIP-associated protein with a death domain
caspase and RIP adapter with death domain

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009950.2NP_034080.1  death domain-containing protein CRADD

    See identical proteins and their annotated locations for NP_034080.1

    Status: PROVISIONAL

    Source sequence(s)
    AC153366, AC153940
    Consensus CDS
    CCDS24135.1
    UniProtKB/Swiss-Prot
    O88843
    UniProtKB/TrEMBL
    Q549T4
    Related
    ENSMUSP00000050295, ENSMUST00000053594
    Conserved Domains (2) summary
    cd08319
    Location:116198
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    95174739..95324345 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513179.1XP_006513242.1  

    See identical proteins and their annotated locations for XP_006513242.1

    UniProtKB/Swiss-Prot
    O88843
    UniProtKB/TrEMBL
    Q549T4
    Conserved Domains (2) summary
    cd08319
    Location:116198
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain
  2. XM_006513182.2XP_006513245.1  

    See identical proteins and their annotated locations for XP_006513245.1

    UniProtKB/Swiss-Prot
    O88843
    UniProtKB/TrEMBL
    Q549T4
    Conserved Domains (2) summary
    cd08319
    Location:116198
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain
  3. XM_006513180.2XP_006513243.1  

    See identical proteins and their annotated locations for XP_006513243.1

    UniProtKB/Swiss-Prot
    O88843
    UniProtKB/TrEMBL
    Q549T4
    Conserved Domains (2) summary
    cd08319
    Location:116198
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain
  4. XM_006513181.2XP_006513244.1  

    See identical proteins and their annotated locations for XP_006513244.1

    UniProtKB/Swiss-Prot
    O88843
    UniProtKB/TrEMBL
    Q549T4
    Conserved Domains (2) summary
    cd08319
    Location:116198
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain
  5. XM_006513178.2XP_006513241.1  

    See identical proteins and their annotated locations for XP_006513241.1

    UniProtKB/Swiss-Prot
    O88843
    UniProtKB/TrEMBL
    Q549T4
    Conserved Domains (2) summary
    cd08319
    Location:116198
    Death_RAIDD; Death domain of RIP-associated ICH-1 homologous protein with a death domain
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain
  6. XM_006513184.2XP_006513247.1  

    See identical proteins and their annotated locations for XP_006513247.1

    UniProtKB/TrEMBL
    Q3UMW0
    Conserved Domains (1) summary
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain
  7. XM_006513183.2XP_006513246.1  

    See identical proteins and their annotated locations for XP_006513246.1

    UniProtKB/TrEMBL
    Q3UMW0
    Conserved Domains (1) summary
    cd08327
    Location:194
    CARD_RAIDD; Caspase activation and recruitment domain of RIP-associated ICH-1 homologous protein with a death domain

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    97149089..97298972 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)