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LOC1269945 sestrin homolog [ Anopheles gambiae (African malaria mosquito) ]

Gene ID: 1269945, updated on 12-Jun-2024

Summary

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Gene symbol
LOC1269945
Gene description
sestrin homolog
Gene type
protein coding
RefSeq status
MODEL
Organism
Anopheles gambiae
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
Orthologs
fruit fly all
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Genomic context

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See LOC1269945 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_12 current idAnoGambNW_F1_1 (GCF_943734735.2) 2 NC_064601.1 (112552335..112584417)

Chromosome 2 - NC_064601.1Genomic Context describing neighboring genes Neighboring gene protein lethal(2)denticleless Neighboring gene mitochondrial import inner membrane translocase subunit Tim10B Neighboring gene Phosphoseryl tRNA kinase Neighboring gene Alg3, alpha-1,3- mannosyltransferase Neighboring gene uncharacterized LOC4576387 Neighboring gene uncharacterized LOC4576388

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_064601.1 Chromosome 2 Reference idAnoGambNW_F1_1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Anopheles gambiae genome: an update. Mongin E, et al. Trends Parasitol, 2004 Feb. PMID 14747013
  2. The genome sequence of the malaria mosquito Anopheles gambiae. Holt RA, et al. Science, 2002 Oct 4. PMID 12364791

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-leucine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to L-leucine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leucine starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to reactive oxygen species IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sestrin homolog
Names
AGAP007169-PA
AGAP007169-PB
sestrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_943734735.2-RS_2023_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference idAnoGambNW_F1_1 Primary Assembly

Genomic

  1. NC_064601.1 Reference idAnoGambNW_F1_1 Primary Assembly

    Range
    112552335..112584417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_061642286.1 → XP_061498270.1  sestrin homolog

    UniProtKB/TrEMBL
    Q7PTB1

  2. XM_308599.5 → XP_308599.4  sestrin homolog

    See identical proteins and their annotated locations for XP_308599.4

    UniProtKB/TrEMBL
    Q7PTB1
    Conserved Domains (1) summary
    pfam04636
    Location:4 → 440
    PA26; PA26 p53-induced protein (sestrin)

  3. XM_061642283.1 → XP_061498267.1  sestrin homolog

    UniProtKB/TrEMBL
    Q7PTB1

  4. XM_061642284.1 → XP_061498268.1  sestrin homolog

    UniProtKB/TrEMBL
    Q7PTB1

  5. XM_001687976.2 → XP_001688028.1  sestrin homolog

    See identical proteins and their annotated locations for XP_001688028.1

    UniProtKB/TrEMBL
    Q7PTB1
    Conserved Domains (1) summary
    pfam04636
    Location:4 → 440
    PA26; PA26 p53-induced protein (sestrin)

  6. XM_061642285.1 → XP_061498269.1  sestrin homolog

    UniProtKB/TrEMBL
    Q7PTB1
Nucleotide Protein Strain
Heading Accession and Version

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