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Gr10a Gustatory receptor 10a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 117501, updated on 10-May-2024

Summary

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Official Symbol
Gr10aprovided by FlyBase
Official Full Name
Gustatory receptor 10aprovided by FlyBase
Primary source
FLYBASE:FBgn0045502
Locus tag
Dmel_CG32664
See related
AllianceGenome:FB:FBgn0045502
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32664; Dmel\CG32664; gr10a; GR10a; Gr10B1
Summary
Predicted to enable sweet taste receptor activity. Predicted to be involved in sensory perception of taste. Predicted to be integral component of membrane. Predicted to be active in axon; dendrite; and neuronal cell body. Is expressed in adult olfactory receptor neuron Or10a; gustatory receptor neuron B2 of the terminal organ dorsolateral group; gustatory receptor neuron of terminal organ dorsolateral group; larval gnathal ganglion; and third segment of antenna. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Gr10a in Genome Data Viewer
Location:
10B10-10B10; 1-34 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11413467..11417422, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11307500..11309866, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 10b Neighboring gene Odorant receptor 10a Neighboring gene Glutamine synthetase 2 Neighboring gene Ecotropic viral integration site 5 Neighboring gene Sphingosine kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reduced X-linked rare polymorphism in males in comparison to females of Drosophila melanogaster. Takahashi KH, et al. J Hered, 2009 Jan-Feb. PMID 18836147
  2. Two chemosensory receptors together mediate carbon dioxide detection in Drosophila. Jones WD, et al. Nature, 2007 Jan 4. PMID 17167414
  3. Bitter taste receptors confer diverse functions to neurons. Delventhal R, et al. Elife, 2016 Feb 15. PMID 26880560, Free PMC Article
  4. Caffeine Taste Signaling in Drosophila Larvae. Apostolopoulou AA, et al. Front Cell Neurosci, 2016. PMID 27555807, Free PMC Article
  5. High amylose starch consumption induces obesity in Drosophila melanogaster and metformin partially prevents accumulation of storage lipids and shortens lifespan of the insects. Abrat OB, et al. Comp Biochem Physiol A Mol Integr Physiol, 2018 Jan. PMID 29054808

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sweet taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables taste receptor activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in sensory perception of taste IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of taste NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
gustatory receptor 10a
Names
CG32664-PB
Gr10a-PB
gustatory receptor 10B1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11413467..11417422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167283.3 → NP_727523.1  gustatory receptor 10a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727523.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1C3K6, P58950
    Related
    FBpp0312371
    Conserved Domains (1) summary
    pfam08395
    Location:20 → 402
    7tm_7; 7tm Chemosensory receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P58950.1 P58950

Gene LinkOut

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