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REL REL proto-oncogene, NF-kB subunit [ Athene cunicularia (burrowing owl) ]

Gene ID: 113478750, updated on 15-Mar-2024

Summary

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Gene symbol
REL
Gene description
REL proto-oncogene, NF-kB subunit
See related
Ensembl:ENSACUG00000011970
Gene type
protein coding
RefSeq status
MODEL
Organism
Athene cunicularia
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Strigiformes; Strigidae; Athene
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
15
Annotation release Status Assembly Chr Location
100 current athCun1 (GCF_003259725.1) 3 Unlocalized Scaffold NW_020799097.1 (116290133..116333809)

NW_020799097.1Genomic Context describing neighboring genes Neighboring gene BCL11 transcription factor A Neighboring gene poly(A) polymerase gamma Neighboring gene pseudouridine synthase 10 Neighboring gene peroxisomal biogenesis factor 13 Neighboring gene SANT and BTB domain regulator of CSR

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020799097 Chromosome 3 Unlocalized Scaffold Reference athCun1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene c-Rel

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Athene cunicularia Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference athCun1

Genomic

  1. NW_020799097.1 Reference athCun1

    Range
    116290133..116333809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026846201.1 → XP_026702002.1  proto-oncogene c-Rel

    UniProtKB/TrEMBL
    A0A663N2M4

  2. XM_026846202.1 → XP_026702003.1  proto-oncogene c-Rel

    UniProtKB/TrEMBL
    A0A663N2M4
    Conserved Domains (2) summary
    cd01177
    Location:166 → 261
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
    cl08275
    Location:1 → 159
    RHD-n; N-terminal sub-domain of the Rel homology domain (RHD)

  3. XM_026846203.1 → XP_026702004.1  proto-oncogene c-Rel

    UniProtKB/TrEMBL
    A0A663N2M4
    Related
    ENSACUP00000017823.1, ENSACUT00000019016.1
Nucleotide Protein
Heading Accession and Version

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