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OPTN optineurin [ Callorhinus ursinus (northern fur seal) ]

Gene ID: 112810004, updated on 15-Mar-2024

Summary

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Gene symbol
OPTN
Gene description
optineurin
See related
EnsemblRapid:ENSCURG00000021558
Gene type
protein coding
RefSeq status
MODEL
Organism
Callorhinus ursinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Callorhinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current ASM326570v1 (GCF_003265705.1) Unplaced Scaffold NW_020313057.1 (4048935..4100353, complement)

NW_020313057.1Genomic Context describing neighboring genes Neighboring gene phytanoyl-CoA 2-hydroxylase Neighboring gene minichromosome maintenance 10 replication initiation factor Neighboring gene upper zone of growth plate and cartilage matrix associated Neighboring gene uncharacterized LOC112810006 Neighboring gene tubulin alpha-1A chain-like Neighboring gene coiled-coil domain containing 3 Neighboring gene peptidyl-prolyl cis-trans isomerase D pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020313057 Unplaced Scaffold Reference ASM326570v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables K63-linked polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi ribbon formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
optineurin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Callorhinus ursinus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM326570v1 Primary Assembly

Genomic

  1. NW_020313057.1 Reference ASM326570v1 Primary Assembly

    Range
    4048935..4100353 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025853437.1 → XP_025709222.1  optineurin isoform X1

    UniProtKB/TrEMBL
    A0A3Q7MPY7
    Related
    ENSCURP00000035072.1, ENSCURT00000040080.1
    Conserved Domains (3) summary
    cd09803
    Location:417 → 503
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:200 → 483
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_025853435.1 → XP_025709220.1  optineurin isoform X1

    UniProtKB/TrEMBL
    A0A3Q7MPY7
    Conserved Domains (3) summary
    cd09803
    Location:417 → 503
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:200 → 483
    SMC_N; RecF/RecN/SMC N terminal domain

  3. XM_025853442.1 → XP_025709227.1  optineurin isoform X4

    UniProtKB/TrEMBL
    A0A3Q7MQ79
    Conserved Domains (3) summary
    cd09803
    Location:415 → 501
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:234 → 514
    SMC_N; RecF/RecN/SMC N terminal domain

  4. XM_025853441.1 → XP_025709226.1  optineurin isoform X3

    UniProtKB/TrEMBL
    A0A3Q7P0U6
    Conserved Domains (3) summary
    cd09803
    Location:415 → 501
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:198 → 481
    SMC_N; RecF/RecN/SMC N terminal domain

  5. XM_025853440.1 → XP_025709225.1  optineurin isoform X2

    UniProtKB/TrEMBL
    A0A3Q7MQ85
    Conserved Domains (3) summary
    cd09803
    Location:417 → 503
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:236 → 516
    SMC_N; RecF/RecN/SMC N terminal domain

  6. XM_025853434.1 → XP_025709219.1  optineurin isoform X1

    UniProtKB/TrEMBL
    A0A3Q7MPY7
    Related
    ENSCURP00000035067.1, ENSCURT00000040075.1
    Conserved Domains (3) summary
    cd09803
    Location:417 → 503
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:200 → 483
    SMC_N; RecF/RecN/SMC N terminal domain

  7. XM_025853438.1 → XP_025709223.1  optineurin isoform X1

    UniProtKB/TrEMBL
    A0A3Q7MPY7
    Conserved Domains (3) summary
    cd09803
    Location:417 → 503
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:200 → 483
    SMC_N; RecF/RecN/SMC N terminal domain

  8. XM_025853439.1 → XP_025709224.1  optineurin isoform X1

    UniProtKB/TrEMBL
    A0A3Q7MPY7
    Conserved Domains (3) summary
    cd09803
    Location:417 → 503
    UBAN; polyubiquitin binding domain of NEMO and related proteins
    pfam11577
    Location:37 → 104
    NEMO; NF-kappa-B essential modulator NEMO
    cl25732
    Location:200 → 483
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein
Heading Accession and Version

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