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NCF1 neutrophil cytosolic factor 1 [ Canis lupus dingo (dingo) ]

Gene ID: 112646127, updated on 15-Mar-2024

Summary

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Gene symbol
NCF1
Gene description
neutrophil cytosolic factor 1
See related
Ensembl:ENSCAFG00020005887
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
11
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 6 NC_064248.1 (5472261..5489273, complement)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 6 Unlocalized Scaffold NW_023365097.1 (5594952..5611664, complement)

Chromosome 6 - NC_064248.1Genomic Context describing neighboring genes Neighboring gene chromobox protein homolog 3-like Neighboring gene general transcription factor II-I repeat domain-containing protein 2 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC125755221 Neighboring gene general transcription factor IIi Neighboring gene transmembrane protein 258-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables superoxide-generating NADPH oxidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in respiratory burst IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutrophil cytosol factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064248.1 Reference ASM325472v2

    Range
    5472261..5489273 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025425759.3 → XP_025281544.1  neutrophil cytosol factor 1

    UniProtKB/TrEMBL
    A0A8C0JZK7, A0A8C0RKZ9, A0A8I3MJA0
    Related
    ENSCAFP00020007317.1
    Conserved Domains (5) summary
    cd06887
    Location:6 → 123
    PX_p47phox; The phosphoinositide binding Phox Homology domain of the p47phox subunit of NADPH oxidase
    cd12021
    Location:160 → 212
    SH3_p47phox_1; First or N-terminal Src homology 3 domain of the p47phox subunit of NADPH oxidase, also called Neutrophil Cytosolic Factor 1
    cd12022
    Location:230 → 282
    SH3_p47phox_2; Second or C-terminal Src homology 3 domain of the p47phox subunit of NADPH oxidase, also called Neutrophil Cytosolic Factor 1
    pfam08944
    Location:360 → 391
    p47_phox_C; NADPH oxidase subunit p47Phox, C terminal domain
    pfam16621
    Location:282 → 331
    NECFESHC; SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1
Nucleotide Protein
Heading Accession and Version

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