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PCSK1 proprotein convertase subtilisin/kexin type 1 [ Theropithecus gelada (gelada) ]

Gene ID: 112626110, updated on 15-Mar-2024

Summary

Gene symbol
PCSK1
Gene description
proprotein convertase subtilisin/kexin type 1
See related
Ensembl:ENSTGEG00000004486
Gene type
protein coding
RefSeq status
MODEL
Organism
Theropithecus gelada
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Theropithecus
Orthologs
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Genomic context

Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
100 current Tgel_1.0 (GCF_003255815.1) 6 NC_037673.1 (91853296..91896775, complement)

Chromosome 6 - NC_037673.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene heterogeneous nuclear ribonucleoprotein C pseudogene Neighboring gene calpastatin Neighboring gene endoplasmic reticulum aminopeptidase 1 Neighboring gene endoplasmic reticulum aminopeptidase 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_037673.1 Chromosome 6 Reference Tgel_1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
neuroendocrine convertase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Theropithecus gelada Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tgel_1.0 Primary Assembly

Genomic

  1. NC_037673.1 Reference Tgel_1.0 Primary Assembly

    Range
    91853296..91896775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025387924.1XP_025243709.1  neuroendocrine convertase 1

    UniProtKB/TrEMBL
    A0A8D2EJ25
    Related
    ENSTGEP00000005401.1, ENSTGET00000006542.1
    Conserved Domains (4) summary
    cd04059
    Location:121415
    Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
    pfam01483
    Location:504591
    P_proprotein; Proprotein convertase P-domain
    pfam12177
    Location:711747
    Proho_convert; Prohormone convertase enzyme
    pfam16470
    Location:34110
    S8_pro-domain; Peptidase S8 pro-domain
  2. XM_025387925.1XP_025243710.1  neuroendocrine convertase 1

    UniProtKB/TrEMBL
    A0A8D2EJ25
    Conserved Domains (4) summary
    cd04059
    Location:121415
    Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
    pfam01483
    Location:504591
    P_proprotein; Proprotein convertase P-domain
    pfam12177
    Location:711747
    Proho_convert; Prohormone convertase enzyme
    pfam16470
    Location:34110
    S8_pro-domain; Peptidase S8 pro-domain