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igf1r insulin like growth factor 1 receptor [ Salvelinus sp. IW2-2015 ]

Gene ID: 111962390, updated on 13-Aug-2024

Summary

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Gene symbol
igf1r
Gene description
insulin like growth factor 1 receptor
Gene type
protein coding
RefSeq status
MODEL
Organism
Salvelinus sp. IW2-2015
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salvelinus
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Genomic context

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Location:
chromosome: LG4q.1:29
Exon count:
19
Annotation release Status Assembly LG Location
101 current ASM291031v2 (GCF_002910315.2) LG4q.1:29 NC_036842.1 (65801203..65839871)

Linkage Group LG4q.1:29 - NC_036842.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 169 member B Neighboring gene actin related protein 2/3 complex inhibitor Neighboring gene synemin, intermediate filament protein Neighboring gene tetratricopeptide repeat domain 23

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_036842.1 Chromosome LG4q.1:29 Reference ASM291031v2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor substrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of insulin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-like growth factor 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Salvelinus alpinus Annotation Release 101

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM291031v2 Primary Assembly

Genomic

  1. NC_036842.1 Reference ASM291031v2 Primary Assembly

    Range
    65801203..65839871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023985451.1 → XP_023841219.1  insulin-like growth factor 1 receptor isoform X1

    Conserved Domains (5) summary
    cd00063
    Location:519 → 599
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam01030
    Location:30 → 144
    Recep_L_domain; Receptor L domain
    pfam04959
    Location:966 → 1033
    ARS2; Arsenite-resistance protein 2
    cl21453
    Location:668 → 960
    PKc_like; Protein Kinases, catalytic domain
    cl21522
    Location:289 → 326
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  2. XM_023985452.1 → XP_023841220.1  insulin-like growth factor 1 receptor isoform X2

    Conserved Domains (4) summary
    cd00063
    Location:519 → 599
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam01030
    Location:30 → 144
    Recep_L_domain; Receptor L domain
    cl21453
    Location:668 → 953
    PKc_like; Protein Kinases, catalytic domain
    cl21522
    Location:289 → 326
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Nucleotide Protein
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