U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MBTPS2 membrane bound transcription factor peptidase, site 2 [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

Gene ID: 111534807, updated on 15-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
MBTPS2
Gene description
membrane bound transcription factor peptidase, site 2
See related
Ensembl:ENSPTEG00000011182
Gene type
protein coding
RefSeq status
MODEL
Organism
Piliocolobus tephrosceles
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
Also known as
YY2
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Y
Exon count:
13
Annotation release Status Assembly Chr Location
102 current ASM277652v3 (GCF_002776525.3) Y NC_045456.1 (1606730..1665880, complement)
100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019359082.1 (128454..148240)

Chromosome Y - NC_045456.1Genomic Context describing neighboring genes Neighboring gene phosphate regulating endopeptidase X-linked Neighboring gene spermine synthase Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene dnaJ homolog subfamily A member 1 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein intracellular domain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of PcG protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
membrane-bound transcription factor site-2 protease
Names
YY2 transcription factor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM277652v3

Genomic

  1. NC_045456.1 Reference ASM277652v3

    Range
    1606730..1665880 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026451879.1 → XP_026307664.1  membrane-bound transcription factor site-2 protease isoform X2

    UniProtKB/TrEMBL
    A0A8C9GU70, A0A8C9GUL6
    Related
    ENSPTEP00000009851.1, ENSPTET00000014976.1
    Conserved Domains (2) summary
    cd06162
    Location:18 → 230
    S2P-M50_PDZ_SREBP; Sterol regulatory element-binding protein (SREBP) Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50A), regulates intramembrane proteolysis (RIP) of SREBP and is part of a signal transduction mechanism involved in sterol and lipid ...
    pfam02163
    Location:160 → 501
    Peptidase_M50; Peptidase family M50

  2. XM_026451880.1 → XP_026307665.1  membrane-bound transcription factor site-2 protease isoform X3

    UniProtKB/TrEMBL
    A0A8C9GU70
    Conserved Domains (2) summary
    cd06162
    Location:18 → 230
    S2P-M50_PDZ_SREBP; Sterol regulatory element-binding protein (SREBP) Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50A), regulates intramembrane proteolysis (RIP) of SREBP and is part of a signal transduction mechanism involved in sterol and lipid ...
    pfam02163
    Location:160 → 501
    Peptidase_M50; Peptidase family M50

  3. XM_023201318.2 → XP_023057086.1  membrane-bound transcription factor site-2 protease isoform X1

    UniProtKB/TrEMBL
    A0A8C9GSE9
    Related
    ENSPTEP00000009858.1, ENSPTET00000014986.1
    Conserved Domains (3) summary
    cd06162
    Location:18 → 229
    S2P-M50_PDZ_SREBP; Sterol regulatory element-binding protein (SREBP) Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50A), regulates intramembrane proteolysis (RIP) of SREBP and is part of a signal transduction mechanism involved in sterol and lipid ...
    COG5048
    Location:510 → 599
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:512 → 532
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.