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MPL MPL proto-oncogene, thrombopoietin receptor [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111175412, updated on 15-Mar-2024

Summary

Gene symbol
MPL
Gene description
MPL proto-oncogene, thrombopoietin receptor
See related
Ensembl:ENSDLEG00000021691
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
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Genomic context

See MPL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098066.1 (11573965..11586603)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160870.1 (11575049..11587687)

NW_022098066.1Genomic Context describing neighboring genes Neighboring gene hypoxanthine-guanine phosphoribosyltransferase-like Neighboring gene tyrosine kinase with immunoglobulin like and EGF like domains 1 Neighboring gene cell division cycle 20 Neighboring gene ELOVL fatty acid elongase 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098066.1 Reference ASM228892v3 Primary Assembly

    Range
    11573965..11586603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022574978.1XP_022430686.1  thrombopoietin receptor

    UniProtKB/TrEMBL
    A0A2Y9NCN1
    Related
    ENSDLEP00000030475.1, ENSDLET00000033464.1
    Conserved Domains (2) summary
    cd00063
    Location:394484
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09067
    Location:25128
    EpoR_lig-bind; Erythropoietin receptor, ligand binding