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traf6 TNF receptor-associated factor 6 [ Acanthochromis polyacanthus (spiny chromis) ]

Gene ID: 110959301, updated on 15-Mar-2024

Summary

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Gene symbol
traf6
Gene description
TNF receptor-associated factor 6
See related
Ensembl:ENSAPOG00000006353
Gene type
protein coding
RefSeq status
MODEL
Organism
Acanthochromis polyacanthus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Pomacentridae; Acanthochromis
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_02 current KAUST_Apoly_ChrSc (GCF_021347895.1) 2 NC_067114.1 (44456736..44469999)

Chromosome 2 - NC_067114.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110959304 Neighboring gene tetratricopeptide repeat domain 17 Neighboring gene transient receptor potential cation channel, subfamily M, member 5 Neighboring gene cyclin dependent kinase inhibitor 1Ca

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067114.1 Chromosome 2 Reference KAUST_Apoly_ChrSc

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_021347895.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference KAUST_Apoly_ChrSc

Genomic

  1. NC_067114.1 Reference KAUST_Apoly_ChrSc

    Range
    44456736..44469999
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022206109.2 → XP_022061801.1  TNF receptor-associated factor 6

    UniProtKB/TrEMBL
    A0A3Q1G596
    Related
    ENSAPOP00000024104.1
    Conserved Domains (3) summary
    cd03776
    Location:395 → 542
    MATH_TRAF6; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF6 subfamily, TRAF domain, C-terminal MATH subdomain; composed of proteins with similarity to human TRAF6, including the Drosophila protein DTRAF2. TRAF molecules serve as adapter ...
    pfam02176
    Location:213 → 270
    zf-TRAF; TRAF-type zinc finger
    cd16643
    Location:76 → 133
    mRING-HC-C3HC3D_TRAF6; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) and similar proteins
Nucleotide Protein
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