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DERL2 derlin 2 [ Neomonachus schauinslandi (Hawaiian monk seal) ]

Gene ID: 110584548, updated on 15-Mar-2024

Summary

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Gene symbol
DERL2
Gene description
derlin 2
See related
EnsemblRapid:ENSNSCG00000004274
Gene type
protein coding
RefSeq status
MODEL
Organism
Neomonachus schauinslandi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Neomonachus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
7
Annotation release Status Assembly Chr Location
101 current ASM220157v2 (GCF_002201575.2) 15 NC_058417.1 (1293969..1304113)
100 previous assembly ASM220157v1 (GCF_002201575.1) Unplaced Scaffold NW_018734354.1 (11644651..11654263, complement)

Chromosome 15 - NC_058417.1Genomic Context describing neighboring genes Neighboring gene WSC domain containing 1 Neighboring gene NLR family pyrin domain containing 1 Neighboring gene MIS12 kinetochore complex component Neighboring gene DEAH-box helicase 33 Neighboring gene complement C1q binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables misfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-specific protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Hrd1p ubiquitin ligase ERAD-L complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
derlin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neomonachus schauinslandi Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM220157v2

Genomic

  1. NC_058417.1 Reference ASM220157v2

    Range
    1293969..1304113
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021694632.2 → XP_021550307.1  derlin-2 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9HFA6
    Related
    ENSNSCP00000005108.1
    Conserved Domains (1) summary
    pfam04511
    Location:13 → 203
    DER1; Der1-like family

  2. XM_044921529.1 → XP_044777464.1  derlin-2 isoform X1

    UniProtKB/TrEMBL
    A0A8M1MZ39
    Conserved Domains (1) summary
    cl21536
    Location:11 → 190
    Rhomboid; Rhomboid family

  3. XM_044921532.1 → XP_044777467.1  derlin-2 isoform X4

    UniProtKB/TrEMBL
    A0A8M1MUD6

  4. XM_044921530.1 → XP_044777465.1  derlin-2 isoform X2

    UniProtKB/TrEMBL
    A0A8M1MW69
    Conserved Domains (1) summary
    cl21536
    Location:11 → 189
    Rhomboid; Rhomboid family
Nucleotide Protein
Heading Accession and Version

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