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SOCS5 suppressor of cytokine signaling 5 [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110395928, updated on 11-Apr-2024

Summary

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Gene symbol
SOCS5
Gene description
suppressor of cytokine signaling 5
See related
Ensembl:ENSNMEG00000016408
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
4
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) 3 NC_034411.1 (26773214..26805627)

Chromosome 3 - NC_034411.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol glycan anchor biosynthesis class F Neighboring gene uncharacterized LOC110395929 Neighboring gene CXXC repeat containing interactor of PDZ3 domain Neighboring gene uncharacterized LOC110395930 Neighboring gene uncharacterized LOC110397201 Neighboring gene uncharacterized LOC110396921 Neighboring gene multiple coagulation factor deficiency 2, ER cargo receptor complex subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034411.1 Chromosome 3 Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of cytokine signaling 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034411.1 Reference NumMel1.0 Primary Assembly

    Range
    26773214..26805627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021391009.1 → XP_021246684.1  suppressor of cytokine signaling 5

    Related
    ENSNMEP00000018939.1, ENSNMET00000027814.1
    Conserved Domains (3) summary
    cd03739
    Location:479 → 535
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 193
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain

  2. XM_021391010.1 → XP_021246685.1  suppressor of cytokine signaling 5

    Conserved Domains (3) summary
    cd03739
    Location:479 → 535
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:146 → 193
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:370 → 470
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
Heading Accession and Version

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