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Bcr BCR activator of RhoGEF and GTPase [ Mus pahari (shrew mouse) ]

Gene ID: 110326865, updated on 15-Mar-2024

Summary

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Gene symbol
Bcr
Gene description
BCR activator of RhoGEF and GTPase
See related
Ensembl:MGP_PahariEiJ_G0030852
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus pahari
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Coelomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
23
Annotation release Status Assembly Chr Location
101 current PAHARI_EIJ_v1.1 (GCF_900095145.1) 9 NC_034598.1 (39764254..39886422)

Chromosome 9 - NC_034598.1Genomic Context describing neighboring genes Neighboring gene radial spoke head 14 homolog Neighboring gene G protein subunit alpha z Neighboring gene RAB36, member RAS oncogene family Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 like Neighboring gene adenosine A2a receptor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034598.1 Chromosome 9 Reference PAHARI_EIJ_v1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breakpoint cluster region protein
Names
BCR, RhoGEF and GTPase activating protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus pahari Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PAHARI_EIJ_v1.1

Genomic

  1. NC_034598.1 Reference PAHARI_EIJ_v1.1

    Range
    39764254..39886422
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021205482.2 → XP_021061141.1  breakpoint cluster region protein

    Related
    MGP_PahariEiJ_P0086565, MGP_PahariEiJ_T0086565.1
    Conserved Domains (5) summary
    cd08686
    Location:912 → 1032
    C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
    cd04387
    Location:1051 → 1251
    RhoGAP_Bcr; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, a Ser/Thr ...
    pfam09036
    Location:3 → 75
    Bcr-Abl_Oligo; Bcr-Abl oncoprotein oligomerization domain
    pfam00621
    Location:501 → 688
    RhoGEF; RhoGEF domain
    cl17171
    Location:683 → 876
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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