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Sh2d3c SH2 domain containing 3C [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110310516, updated on 15-Mar-2024

Summary

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Gene symbol
Sh2d3c
Gene description
SH2 domain containing 3C
See related
Ensembl:MGP_CAROLIEiJ_G0023446
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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See Sh2d3c in Genome Data Viewer
Location:
chromosome: 2
Exon count:
15
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 2 NC_034571.1 (28594865..28629644)

Chromosome 2 - NC_034571.1Genomic Context describing neighboring genes Neighboring gene folylpolyglutamate synthase Neighboring gene cyclin dependent kinase 9 Neighboring gene uncharacterized LOC110310535 Neighboring gene tetratricopeptide repeat domain 16 Neighboring gene cilia and flagella associated protein 157 Neighboring gene peptidyl-tRNA hydrolase 1 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034571.1 Chromosome 2 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH2 domain-containing protein 3C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034571.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    28594865..28629644
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021183545.1 → XP_021039204.1  SH2 domain-containing protein 3C isoform X1

    UniProtKB/TrEMBL
    A0A6P5R440
    Related
    MGP_CAROLIEiJ_P0051192, MGP_CAROLIEiJ_T0051192.1
    Conserved Domains (2) summary
    cd10337
    Location:208 → 342
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:579 → 756
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  2. XM_029474378.1 → XP_029330238.1  SH2 domain-containing protein 3C isoform X2

    UniProtKB/TrEMBL
    A0A6P7QMJ8

  3. XM_029474379.1 → XP_029330239.1  SH2 domain-containing protein 3C isoform X3

    UniProtKB/TrEMBL
    A0A6P7QUA9

  4. XM_021183553.2 → XP_021039212.1  SH2 domain-containing protein 3C isoform X4

    UniProtKB/TrEMBL
    A0A6P5R445
    Related
    MGP_CAROLIEiJ_P0051194, MGP_CAROLIEiJ_T0051194.1
    Conserved Domains (2) summary
    cd10337
    Location:56 → 190
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:427 → 604
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  5. XM_029474380.1 → XP_029330240.1  SH2 domain-containing protein 3C isoform X5

    UniProtKB/TrEMBL
    A0A6P7R029
    Conserved Domains (2) summary
    cd10337
    Location:55 → 189
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:426 → 603
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
Nucleotide Protein
Heading Accession and Version

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