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Setdb2 SET domain bifurcated histone lysine methyltransferase 2 [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110309030, updated on 15-Mar-2024

Summary

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Gene symbol
Setdb2
Gene description
SET domain bifurcated histone lysine methyltransferase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
23
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 14 NC_034583.1 (50586472..50672335, complement)

Chromosome 14 - NC_034583.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110309812 Neighboring gene RCC1 and BTB domain containing protein 1 Neighboring gene PHD finger protein 11 Neighboring gene calcium binding protein 39 like Neighboring gene cytidine and dCMP deaminase domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034583.1 Chromosome 14 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heterochromatin organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA methylation-dependent heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETDB2
Names
SET domain bifurcated 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034583.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    50586472..50672335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021181369.2 → XP_021037028.2  LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETDB2

    UniProtKB/TrEMBL
    A0A6P5R4L3
    Conserved Domains (3) summary
    cd01395
    Location:152 → 212
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl22851
    Location:700 → 813
    PHD_SF; PHD finger superfamily
    cl40432
    Location:210 → 687
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
Nucleotide Protein
Heading Accession and Version

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