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Psen2 presenilin 2 [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110298007, updated on 15-Mar-2024

Summary

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Gene symbol
Psen2
Gene description
presenilin 2
See related
Ensembl:MGP_CAROLIEiJ_G0014975
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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See Psen2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 1 NC_034570.1 (170081014..170108864, complement)

Chromosome 1 - NC_034570.1Genomic Context describing neighboring genes Neighboring gene CDC42 binding protein kinase alpha Neighboring gene coenzyme Q8A Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene inositol-trisphosphate 3-kinase B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034570.1 Chromosome 1 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ciliary rootlet IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic shaft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
presenilin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034570.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    170081014..170108864 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021167068.2 → XP_021022727.1  presenilin-2 isoform X1

    UniProtKB/TrEMBL
    A0A6P5PVC0
    Related
    MGP_CAROLIEiJ_P0021593, MGP_CAROLIEiJ_T0021593.1
    Conserved Domains (1) summary
    pfam01080
    Location:82 → 438
    Presenilin

  2. XM_029478776.1 → XP_029334636.1  presenilin-2 isoform X2

    UniProtKB/TrEMBL
    A0A6P7RBR2
    Related
    MGP_CAROLIEiJ_P0021599, MGP_CAROLIEiJ_T0021599.1

  3. XM_021167065.1 → XP_021022724.1  presenilin-2 isoform X1

    UniProtKB/TrEMBL
    A0A6P5PVC0
    Related
    MGP_CAROLIEiJ_P0021596, MGP_CAROLIEiJ_T0021596.1
    Conserved Domains (1) summary
    pfam01080
    Location:82 → 438
    Presenilin
Nucleotide Protein
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