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Pde2a phosphodiesterase 2A [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110297586, updated on 18-Sep-2024

Summary

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Gene symbol
Pde2a
Gene description
phosphodiesterase 2A
See related
Ensembl:MGP_CAROLIEiJ_G0030062
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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See Pde2a in Genome Data Viewer
Location:
chromosome: 7
Exon count:
35
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 7 NC_034576.1 (104096328..104186569)

Chromosome 7 - NC_034576.1Genomic Context describing neighboring genes Neighboring gene StAR related lipid transfer domain containing 10 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Neighboring gene T-cell ecto-ADP-ribosyltransferase 2 Neighboring gene ClpB family mitochondrial disaggregase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034576.1 Chromosome 7 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 3',5'-cyclic-GMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cGMP catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitochondrion organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cGMP-dependent 3',5'-cyclic phosphodiesterase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034576.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    104096328..104186569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029479520.1 → XP_029335380.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X4

    UniProtKB/TrEMBL
    A0A6P7REK9
    Conserved Domains (2) summary
    smart00065
    Location:385 → 534
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:631 → 864
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  2. XM_029479517.1 → XP_029335377.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A6P7R468
    Related
    MGP_CAROLIEiJ_P0081001, MGP_CAROLIEiJ_T0081001.1

  3. XM_029479518.1 → XP_029335378.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X2

    UniProtKB/TrEMBL
    A0A6P7R2I4
    Related
    MGP_CAROLIEiJ_P0081000, MGP_CAROLIEiJ_T0081000.1

  4. XM_021166409.1 → XP_021022068.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3

    UniProtKB/TrEMBL
    A0A6P7R7I0
    Conserved Domains (2) summary
    smart00065
    Location:389 → 538
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:635 → 868
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  5. XM_029479523.1 → XP_029335383.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X6

    UniProtKB/TrEMBL
    A0A6P7R2I9

  6. XM_029479521.1 → XP_029335381.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X5

    UniProtKB/TrEMBL
    A0A6P7RE23

  7. XM_029479519.1 → XP_029335379.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3

    UniProtKB/TrEMBL
    A0A6P7R7I0
    Conserved Domains (2) summary
    smart00065
    Location:389 → 538
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:635 → 868
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  8. XM_021166410.1 → XP_021022069.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X4

    UniProtKB/TrEMBL
    A0A6P7REK9
    Related
    MGP_CAROLIEiJ_P0081003, MGP_CAROLIEiJ_T0081003.1
    Conserved Domains (2) summary
    smart00065
    Location:385 → 534
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:631 → 864
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  9. XM_029479522.1 → XP_029335382.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X5

    UniProtKB/TrEMBL
    A0A6P7RE23
Nucleotide Protein
Heading Accession and Version

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