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SOCS5 suppressor of cytokine signaling 5 [ Phascolarctos cinereus (koala) ]

Gene ID: 110218504, updated on 11-Apr-2024

Summary

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Gene symbol
SOCS5
Gene description
suppressor of cytokine signaling 5
See related
Ensembl:ENSPCIG00000026010
Gene type
protein coding
RefSeq status
MODEL
Organism
Phascolarctos cinereus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos
Orthologs
human mouse all
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Genomic context

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See SOCS5 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
6
Annotation release Status Assembly Chr Location
100 current phaCin_unsw_v4.1 (GCF_002099425.1) Unplaced Scaffold NW_018344041.1 (8762784..8846961)

NW_018344041.1Genomic Context describing neighboring genes Neighboring gene ras homolog family member Q Neighboring gene phosphatidylinositol glycan anchor biosynthesis class F Neighboring gene CXXC repeat containing interactor of PDZ3 domain Neighboring gene 40S ribosomal protein S4-like Neighboring gene 40S ribosomal protein S2 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018344041 Unplaced Scaffold Reference phaCin_unsw_v4.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of cytokine signaling 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phascolarctos cinereus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference phaCin_unsw_v4.1 Primary Assembly

Genomic

  1. NW_018344041.1 Reference phaCin_unsw_v4.1 Primary Assembly

    Range
    8762784..8846961
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021001249.1 → XP_020856908.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A6P5LK44
    Conserved Domains (3) summary
    cd03739
    Location:482 → 537
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:147 → 194
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:373 → 473
    SH2; Src homology 2 (SH2) domain

  2. XM_021001246.1 → XP_020856905.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A6P5LK44
    Conserved Domains (3) summary
    cd03739
    Location:482 → 537
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:147 → 194
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:373 → 473
    SH2; Src homology 2 (SH2) domain

  3. XM_021001250.1 → XP_020856909.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A6P5LK44
    Conserved Domains (3) summary
    cd03739
    Location:482 → 537
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:147 → 194
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:373 → 473
    SH2; Src homology 2 (SH2) domain

  4. XM_021001247.1 → XP_020856906.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A6P5LK44
    Conserved Domains (3) summary
    cd03739
    Location:482 → 537
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:147 → 194
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:373 → 473
    SH2; Src homology 2 (SH2) domain

  5. XM_021001248.1 → XP_020856907.1  suppressor of cytokine signaling 5

    UniProtKB/TrEMBL
    A0A6P5LK44
    Related
    ENSPCIP00000035156.1, ENSPCIT00000043254.2
    Conserved Domains (3) summary
    cd03739
    Location:482 → 537
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:147 → 194
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:373 → 473
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
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