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Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase [ Castor canadensis (American beaver) ]

Gene ID: 109693442, updated on 14-Mar-2024

Summary

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Gene symbol
Abl2
Gene description
ABL proto-oncogene 2, non-receptor tyrosine kinase
See related
Ensembl:ENSCCNG00000028678
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017871360.1 (462360..562088, complement)

NW_017871360.1Genomic Context describing neighboring genes Neighboring gene Ral GEF with PH domain and SH3 binding motif 2 Neighboring gene angiopoietin like 1 Neighboring gene FAM20B glycosaminoglycan xylosylkinase Neighboring gene calmodulin-like Neighboring gene sterol O-acyltransferase 1 Neighboring gene axonemal dynein light chain domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017871360.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: Abelson tyrosine-protein kinase 2
Names
Abelson tyrosine-protein kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017871360.1 Reference C.can genome v1.0

    Range
    462360..562088 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020174754.1 → XP_020030343.1  LOW QUALITY PROTEIN: Abelson tyrosine-protein kinase 2

    UniProtKB/TrEMBL
    A0A8B7VFA9, A0A8C0ZYW4
    Related
    ENSCCNP00000029897.1, ENSCCNT00000037708.1
    Conserved Domains (4) summary
    smart00808
    Location:960 → 1079
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:169 → 262
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:111 → 164
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:281 → 543
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
Nucleotide Protein
Heading Accession and Version

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