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Tle2 TLE family member 2, transcriptional corepressor [ Castor canadensis (American beaver) ]

Gene ID: 109691039, updated on 14-Mar-2024

Summary

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Gene symbol
Tle2
Gene description
TLE family member 2, transcriptional corepressor
See related
Ensembl:ENSCCNG00000008872
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Orthologs
human mouse all
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Genomic context

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See Tle2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017871081.1 (372845..394245, complement)

NW_017871081.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene TLE family member 6, subcortical maternal complex member Neighboring gene formin-like protein 5 Neighboring gene TLE family member 5, transcriptional modulator Neighboring gene G protein subunit alpha 11

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017871081.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transducin-like enhancer protein 2
Names
transducin like enhancer of split 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017871081.1 Reference C.can genome v1.0

    Range
    372845..394245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020170762.1 → XP_020026351.1  transducin-like enhancer protein 2

    UniProtKB/TrEMBL
    A0A250Y4R0, A0A8B7V309
    Related
    ENSCCNP00000008387.1, ENSCCNT00000011064.1
    Conserved Domains (4) summary
    sd00039
    Location:462 → 501
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl25539
    Location:458 → 742
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl26464
    Location:127 → 368
    Atrophin-1; Atrophin-1 family
Nucleotide Protein
Heading Accession and Version

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